The usual precautions should be observed and the possibility of respiratory depression should be kept in mind. Hydrocodone suppresses the cough reflex; as with all narcotics, caution should be exercised when Lortab 7. Carcinogenesis, Mutagenesis, Impairment of Fertility: No adequate studies have been conducted in animals to determine whether hydrocodone or acetaminophen have a potential for carcinogenesis, mutagenesis, or impairment of fertility. There are no adequate and well-controlled studies in pregnant women.
Babies born to mothers who have been taking opioids regularly prior to delivery will be physically dependent. The withdrawal signs include irritability and excessive crying, tremors, hyperactive reflexes, increased respiratory rate, increased stools, sneezing, yawning, vomiting and fever.
The intensity of the syndrome does not always correlate with the duration of maternal opioid use or dose. There is no consensus on the best method of managing withdrawal. As with all narcotics, administration of this product to the mother shortly before delivery may result in some degree of respiratory depression in the newborn, especially if higher doses are used. Acetaminophen is excreted in breast milk in small amounts, but the significance of its effects on nursing infants is not known.
It is not known whether hydrocodone is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from hydrocodone and acetaminophen, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Safety and effectiveness in the pediatric population have not been established. Clinical studies of hydrocodone bitartrate and acetaminophen tablets did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.
Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Hydrocodone and the major metabolites of acetaminophen are known to be substantially excreted by the kidney.
Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Hydrocodone may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of hydrocodone bitartrate and acetaminophen tablets and observed closely. In severe overdosage, apnea , circulatory collapse, cardiac arrest and death may occur.
Renal tubular necrosis, hypoglycemic coma and thrombocytopenia may also occur. Early symptoms following a potentially hepatotoxic overdose may include: Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48 to 72 hours post-ingestion.
In adults, hepatic toxicity has rarely been reported with acute overdoses of less than 10 grams, or fatalities with less than 15 grams. A single or multiple overdose with hydrocodone and acetaminophen is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended. Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption.
Vomiting should be induced mechanically, or with syrup of ipecac , if the patient is alert adequate pharyngeal and laryngeal reflexes. The first dose should be accompanied by an appropriate cathartic. If repeated doses are used, the cathartic might be included with alternate doses as required. Hypotension is usually hypovolemic and should respond to fluids. You can take a capsule orally every 12 hours. This medication can be used to treat long-term pain problems. In the event of an emergency situation, researchers have found the two medications treat pain equally.
In a study with both drugs, researchers found that both oxycodone and hydrocodone were equally effective at treating pain caused by fractures. Participants experienced equal pain relief 30 and 60 minutes after the medication was taken. However, those who were given hydrocodone experienced constipation more frequently than participants who used oxycodone.
Another study found that the combination of oxycodone and acetaminophen was 1. Cost Both oxycodone and hydrocodone are sold as brand-name drugs and as generic alternatives. Generic medications are cheaper than their brand-name counterparts. For that reason, you may wish to try the generic versions.
Before you do that, consult your doctor. Some generic versions of medications have different ratios of active and inactive ingredients. To be classified as generic by the U. Food and Drug Administration, the drug must include the same strength of active ingredients, but may not have the same amount of inactive ingredients. If you need to use the brand name but find that the price tag is too high, prescription drug insurance and prescription coupons may help reduce your total cost.
To give you a brief overview, an advisory panel to the FDA has recommended tighter restrictions on hydrocodone-containing drugs, which would essentially classify them among the most dangerous prescription medications available to patients. Read More esentially what we are taking is herion in a pill and the cost of taking these pills is so incredibly hugh I wish I had known before I had taken the first.
I'm embarrassed, I feel duped, I feel responsible and cruddy for putting my wife through this. I almost lost my family and Please consider yourself fortunate to have found this site Read More Two months ago my mother in law had emergency surgery and was in the hospital for a month. She was on morphine and then on Hydrocodone. She came home and we are constantly going back and forth to the er. On our last vist she was out of pain meds and told me to take her to the er as she was having chest pains and shortness of breath.
We got her script filled at Monday morning she only had 2 left.
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