CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. In case of such an anaphylactic or severe hypersensitivity reaction, discontinue treatment permanently and institute appropriate therapy.
A careful inquiry should be made concerning previous sensitivities to drugs and other allergens. Usage in Meningitis Since clindamycin does not diffuse adequately into the cerebrospinal fluid, the drug should not be used in the treatment of meningitis.
Precautions General Review of experience to date suggests that a subgroup of older patients with associated severe illness may tolerate diarrhea less well. When clindamycin is indicated in these patients, they should be carefully monitored for change in bowel frequency. Cleocin HCl should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Cleocin HCl should be prescribed with caution in atopic individuals. Indicated surgical procedures should be performed in conjunction with antibiotic therapy. The use of Cleocin HCl occasionally results in overgrowth of nonsusceptible organisms—particularly yeasts. Should superinfections occur, appropriate measures should be taken as indicated by the clinical situation. Clindamycin dosage modification may not be necessary in patients with renal disease.
In patients with moderate to severe liver disease, prolongation of clindamycin half-life has been found. However, it was postulated from studies that when given every eight hours, accumulation should rarely occur. Therefore, dosage modification in patients with liver disease may not be necessary. However, periodic liver enzyme determinations should be made when treating patients with severe liver disease.
Prescribing Cleocin HCl in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
Information for Patients Patients should be counseled that antibacterial drugs, including Cleocin HCl, should only be used to treat bacterial infections. They do not treat viral infections e. Streptococci Serious respiratory tract infections; serious skin and soft tissue infections. Staphylococci Serious respiratory tract infections; serious skin and soft tissue infections.
Pneumococci Serious respiratory tract infections. Bacteriologic studies should be performed to determine the causative organisms and their susceptibility to clindamycin. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Adults Serious infections - to mg every 6 hours. Clostridium difficile colitis Gastrointestinal: Esophageal ulcer has been reported. An unpleasant or metallic taste has been reported after oral administration.
Generalized mild to moderate morbilliform-like maculopapular skin rashes are the most frequently reported adverse reactions. Vesiculobullous rashes, as well as urticaria , have been observed during drug therapy. Cases of Acute Generalized Exanthematous Pustulosis AGEP , erythema multiforme, some resembling Stevens-Johnson syndrome , anaphylactic shock , anaphylactic reaction and hypersensitivity have also been reported. Skin and Mucous Membranes: Pruritus , vaginitis , angioedema and rare instances of exfoliative dermatitis have been reported.
Jaundice and abnormalities in liver function tests have been observed during clindamycin therapy. Transient neutropenia leukopenia and eosinophilia have been reported. Reports of agranulocytosis and thrombocytopenia have been made. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection.
If you have diarrhea that is watery or bloody, stop taking clindamycin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to. To be sure this medication is not causing harmful effects, your blood may need to be tested often.
Your kidney or liver function may also need to be tested. Visit your doctor regularly. If you need surgery, tell the surgeon ahead of time that you are using clindamycin.
You may need to stop using the medicine for a short time. Streptococcus strep is a bacterium often found in the throat, respiratory tract and on the skin. When streptococci get under the skin, they can foster a common skin disease known as impetigo. Impetigo starts out as a little red pin-sized rash resembling tiny pimples. The treatment for impetigo is usually penicillins, but clindamycin is generally used in patients who are allergic to the penicillin group of medications.
This is a common choice for skin infections, and is usually dosed three times a day for 10 days. Here is some information on clindamycin and impetigo: My dentist prescribed clindamycin to me for an absessed tooth. Is there a reaction to sun exposure with this medicine? Sun photo sensitivity is not a common or specific side effect associated with clindamycin Cleocin. However a serious side effect associated with this antibiotic is red, swollen, blistered, or peeling skin, which is not necessarily a reaction from sun exposure.
If you experience a serious skin-related side effect while taking Clindamycin, it is recommended that you contact your doctor or seek medical attention right away.
Is there a remedy for the reaction I am having to clindamycin? Cleocin clindamycin is an antibiotic that is used to treat a variety of infections. If you have a reaction to clindamycin which causes rash, it can be treated with Benadryl diphenhydramine which will help to reduce some of the itching. If the reaction consists of difficulty breathing, stop using the clindamycin and contact your physician as soon as possible.
For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Megan Uehara, PharmD Q: Is clindamycin a penicillin?
Medications can lose their potency and effectiveness as time passes. You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition. Contraindications Cleocin HCl is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis. Clindamycin dosage modification may not be necessary in patients with renal disease. Is clindamycin a penicillin? Therefore, it should be used with caution in patients receiving such agents. Jaundice cleocin abnormalities in liver function tests have been observed during clindamycin hcl. Follow the directions on your prescription label. Esophageal ulcer has been reported. Both tests were negative. Skin and Mucous Membranes: Vesiculobullous rashes, as well as urticariahave been observed during drug therapy. A careful inquiry should be made concerning previous treatments to drugs and other allergens. If the reaction consists of difficulty breathing, cleocin hcl treatment, stop using the clindamycin and contact your physician as soon as flomax tamsulosin no prescription. Cleocin clindamycin is an antibiotic that fights bacteria in the body, cleocin hcl treatment. Generalized mild to moderate morbilliform-like maculopapular skin rashes are the most frequently reported adverse reactions.
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