Do not allow it to freeze. Throw away any unused cefuroxime liquid that is older than 10 days. What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at Overdose symptoms may include seizure black-out or convulsions.
What should I avoid while taking cefuroxime? Antibiotic medicines can cause diarrhea , which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to. Cefuroxime side effects Get emergency medical help if you have signs of an allergic reaction: Call your doctor at once if you have: Common side effects may include: This is not a complete list of side effects and others may occur.
Call your doctor for medical advice about side effects. There are now new data. First-generation cephalosporins have cross-allergy with penicillins, but cross-allergy is negligible with second- and third-generation cephalosporins; this is also most probably true for fourth-generation cephalosporins 8c.
The value of emphasizing the role of chemical structure has been underlined in a case report. Skin tests confirmed that she was allergic to cefuroxime, and the reaction was defined as probable according to the Naranjo probability scale.
A structure-activity relation study was performed using skin testing. She was sensitized to beta-lactam antibiotics with a methoxylimino group, but not to similar compounds that lack this chemical group for example amoxicillin, penicillin G, and penicillin V. Intravenous amoxicillin was well tolerated.
The authors suggested that an approach based on structure-activity relations could help physicians and pharmacists in advising patients with allergic reactions. A similar approach to studying the tolerability of other beta-lactams has been used in patients with a history of aminopenicillin-induced rash 10c. Skin testing was followed by oral challenge to identify beta-lactams that patients with confirmed delayed-type non-immunoglobulin E-mediated allergic hypersensitivity to aminopenicillins could tolerate.
Of 71 patients, 69 tolerated cephalosporins without an aminobenzyl side-chain such as cefpodoxime or cefixime and 51 also tolerated phenoxymethylpenicillin. The authors concluded that skin tests and drug challenge tests can help in determining individual cross-reactivity. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over 2 months after the administration of antibacterial agents.
Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. Potential For Microbial Overgrowth The possibility of superinfections with fungal or bacterial pathogens should be considered during therapy. Development Of Drug-Resistant Bacteria Prescribing CEFTIN either in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Although lifetime studies in animals have not been performed to evaluate carcinogenic potential, no mutagenic activity was found for cefuroxime axetil in a battery of bacterial mutation tests. Positive results were obtained in an in vitro chromosome aberration assay; however, negative results were found in an in vivo micronucleus test at doses up to 1.
There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, CEFTIN should be used during pregnancy only if clearly needed.
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