This medicine can cause unusual results with certain lab tests for glucose sugar in the urine. Tell any doctor who treats you that you are using cefaclor. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Cefaclor will not treat a viral infection such as the flu or a common cold. Store the tablets and capsules at room temperature away from moisture and heat.
Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. Hypertoxin-producing strains of C. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. Prolonged use of cefaclor may result in the overgrowth of nonsusceptible organisms. Careful observation of the patient is essential.
If superinfection occurs during therapy, appropriate measures should be taken. Positive direct Coombs' tests have been reported during treatment with the cephalosporin antibiotics. It should be recognized that a positive Coombs' test may be due to the drug, e. Cefaclor should be administered with caution in the presence of markedly impaired renal function.
Since the half-life of cefaclor in anuria is 2. Clinical experience with cefaclor under such conditions is limited; therefore, careful clinical observation and laboratory studies should be made. Antibiotics, including cephalosporins, should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Carcinogenesis, Mutagenesis, Impairment Of Fertility Studies have not been performed to determine potential for carcinogenicity, mutagenicity, or impairment of fertility. Reproduction studies have been performed in mice and rats at doses up to 12 times the human dose and in ferrets given 3 times the maximum human dose and have revealed no harm to the fetus due to cefaclor.
This includes herbal medicines. Medicines which may interact with or be affected by Cefaclor: Pregnancy Care should be taken when prescribing Cefaclor to pregnant women. Breast-feeding Cefaclor is passed into breast milk and therefore it is advisable to avoid taking Cefaclor whilst breastfeeding. Cefaclor does not affect the ability to drive or operate machinery. Cefaclor contains sucrose If you have been told by your doctor that you have intolerance to some sugars, contact your doctor before taking this medicine.
Causal Relationship Uncertain -- CNS -- Rarely, reversible hyperactivity, agitation, nervousness, insomnia, confusion, hypertonia, dizziness, hallucinations, and somnolence have been reported. Transitory abnormalities in clinical laboratory test results have been reported. Although they were of uncertain etiology, they are listed below to serve as alerting information for the physician. Renal -- Slight elevations in BUN or serum creatinine less than 1 in or abnormal urinalysis less than 1 in Cephalosporin-class Adverse Reactions In addition to the adverse reactions listed above that have been observed in patients treated with cefaclor, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics: Several cephalosporins have been implicated in triggering seizures, particularly in patients with renal impairment when the dosage was not reduced.
If seizures associated with drug therapy occur, the drug should be discontinued. The severity of the epigastric distress and the diarrhea are dose related. If other symptoms are present, it is probable that they are secondary to an underlying disease state, an allergic reaction, or the effects of other intoxication.
Treatment -- To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient.
Unless 5 times the normal dose of cefaclor has been ingested, gastrointestinal decontamination will not be necessary. Protect the patient's airway and support ventilation and perfusion. Meticulously monitor and maintain, within acceptable limits, the patient's vital signs, blood gases, serum electrolytes, etc. It works by stopping the growth of bacteria. This antibiotic only treats bacterial infections. It will not work for viral infections e. Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.
Shake the bottle well before each dose. Take this medication by mouth usually every 8 or 12 hours, or as directed by your doctor. You may take this medicine with food if stomach upset occurs. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.
Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days. Stopping this medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.
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